Research Areas
Our research is organized into four interconnected disciplines, each contributing to our understanding of aging and healthspan extension.
Molecular Sciences
Peptide synthesis, structure-activity relationships, and degradation studies focused on compounds relevant to aging and metabolic health.
Biochemical Systems
Receptor binding assays, enzyme kinetics, and pathway analysis to understand how molecular interventions affect biological systems.
Preclinical Methods
In vitro study protocols, cell-based assays, and standardized RUO methodologies for evaluating compound activity and safety.
Analytical Platforms
HPLC, mass spectrometry, and spectroscopic methods for compound characterization, purity analysis, and stability testing.
Current Research Focus
Metabolic Regulation
Investigating peptides and small molecules that influence metabolic pathways associated with aging and energy homeostasis.
Cellular Senescence
Studying compounds that may affect senescent cell accumulation and the senescence-associated secretory phenotype.
Hormonal Signaling
Characterizing molecules that interact with growth hormone, IGF-1, and related pathways implicated in longevity.
Mitochondrial Function
Exploring interventions that may support mitochondrial health and bioenergetic capacity in aging systems.
Protein Homeostasis
Examining mechanisms of proteostasis and compounds that may influence protein folding and clearance.
Inflammatory Pathways
Investigating the role of chronic inflammation in aging and potential modulators of inflammatory signaling.
Our Approach
LLRI operates with a commitment to reproducibility and transparency. Every study follows documented protocols, and all analytical methods are validated before use. We believe that rigorous methodology is the foundation of meaningful discovery.
Our research generates both scientific knowledge and practical outputs—characterized compounds, validated assays, and documented methods that support the broader research community's work in longevity science.